Dave, Spyware Blaster doesn't remove spyware, or do anything about spyware already on your machine. It will, however, prevent further spyware from getting in, once you've cleaned your machine.
Suggestion: Disable System Restore, go into Safe Mode and run Spybot and Ad Aware. There may well be some nasties lodged in the System Restore folder, which keep reloading each time you restart the PC.
Failing that, run Hijack This and post the results on here.
Ad AwareSpybot S&DSpyware BlasterHijack This