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General Discussion => Science & Nature => Topic started by: sam on December 10, 2009, 01:24

Title: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: sam on December 10, 2009, 01:24
Quote
The low-density lipoprotein receptor (LDLR) has received a lot of attention because of its connection with coronary heart disease and atherosclerosis, but now it appears as if it may have a beneficial influence in degenerative brain diseases. New research, published by Cell Press in the December 10th issue of the journal Neuron, links LDLR with a reduction in brain changes associated with Alzheimer's disease (AD) and suggests a new therapeutic strategy for this incurable disease.

http://www.physorg.com/news179590178.html
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Clive on December 10, 2009, 10:28
I know a few people with Alzheimer's and it's a really dreadful condition to have.  Particularly for those who have to look after them.   :(
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Simon on December 10, 2009, 10:32
Yes, it's almost worse for the carer than the sufferer.  :(
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Rik on December 10, 2009, 10:32
Having been there, I'll second that. :(
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Simon on December 10, 2009, 10:58
Luckily, I haven't been there.  :x:
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Rik on December 10, 2009, 10:59
It's certainly a tough place to be. :(
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: GillE on December 10, 2009, 14:52
My husband looks after Alzheimer sufferers for a living.  It's very poorly paid work and there's no job security, but he loves it.

BBC 2 is showing a very good series about care homes (and most residents in care homes have some form of dementia) by Gerry Robinson.  I saw it the other night and it almost made me weep.  There's so much more that we as a society could and should be doing for these poor people.
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Rik on December 10, 2009, 14:53
I'd agree with you there, Gill. The staff I have met in homes have generally been caring and compassionate, but they are under-resourced and there's insufficient places available as a whole.
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: sam on December 10, 2009, 17:20
I'd agree with you there, Gill. The staff I have met in homes have generally been caring and compassionate, but they are under-resourced and there's insufficient places available as a whole.

and its only going to get worse with an aging population
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Rik on December 10, 2009, 17:24
I'm trying to book my space now. :)
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: GillE on December 10, 2009, 19:15
Don't bother Rik.  If you go down with Alzheimer's it won't bother you.  It'll bother the Dickens out of everyone around you, but you'll be blissfully unaware of that.
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Simon on December 10, 2009, 23:17
No change there, then.   :devil: :)x
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Clive on December 10, 2009, 23:34
I do that all the time Gill.   ;D
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Rik on December 11, 2009, 17:06
No change there, then.   :devil: :)x

 :wahh: ;D
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Simon on December 11, 2009, 20:52
 :santa:
Title: Re: Low-density lipoprotein receptor reduces damage in Alzheimer's brain
Post by: Rik on December 12, 2009, 11:59
 ;D