The Acer partition will be FAT, to judge by what I've seen.
Everyone has their own idea on partitions. Traditionally, I've partitioned C/D/E for System/Apps/Data. That has made backing up easier for me. I tend to use about 50GB for C & D, the balance for E.
My notebook is partitioned this way on a single drive (though not 50GB...). One desktop machine has one drive split to C/D and the second as E (200GB), while this machine has fast 80GB drives for C/D with a 750GB E, and an internal backup drive at F, also 750GB. Using NTFS throughout, I've not seen a problem with the partition size. With the separate physical drives for C/D, I switch the swap file onto D.